Zollinger Ellison Syndrome - Symptom, Treatment and cause of Zollinger Ellison Syndrome

Zollinger Ellison Syndrome Description

(Gastrinoma)

Rare form of severe peptic ulceration in the stomach or small intestine.

Zollinger Ellison Syndrome Cause

A tumor of the pancreas that produces high levels of a hormone which promotes excessive acid production in the stomach.

Zollinger Ellison Syndrome Symptom

Exaggerated symptoms of a peptic ulcer with severe pain in the upper abdomen, bloating, nausea and diarrhea. Usually starts at a younger age than normal for a peptic ulcer.

Investigation

A specific blood test can measure the hormone 'gastrin' which is responsible for stimulating the stomach to produce hydrochloric acid. Other tests include gastroscopy and measuring the amount of acid in the stomach.

Zollinger Ellison Syndrome Treatment

Medications as for normal peptic ulcers, but in higher doses. Surgery is often required to control recurrent ulceration.

Complications

Severe bleeding from ulcers leading to anaemia.

Prognosis of Zollinger Ellison Syndrome

Treatment must be continued lifelong, but is usually successful in controlling the disease.