MorphoeaA limited form of scleroderma which may involve subcutaneous tissue. Early forms of morphoea profunda may manifest as slight septal thickening or there may be extension of morphoea in the dermis into the subcutaneous fat causing marked fibrous thickening of the septa. Atrophy of adnexal structures, a deep inflammatory infiltrate of lymphocytes and plasma cells or presence of lymphoid aggregates in the paraseptal area are diaqnostic features. Symptoms of MorphoeaPatches of thickened skin, which may be rounded or oval in shape, can occur all over the body. They are usually painless but can be itchy. The patches may be lighter or darker than normal skin. Usually there are only a few patches but sometimes the skin changes can be extensive, when the condition is known as generalised morphoea. Treatment of MorphoeaUnfortunately there is no available effective treatment for most cases of morphoea. |
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